2026
Peer-reviewed
Casjens S., Hovanec J., Glaser N., Massag J., Pfrommer L., Opel N., Karch A., Muellmann S., Moor I., Gekle M., Girndt M., Hettmer S., Höll J.I., Heuser M., Frese T., Mikolajczyk R. & Behrens T. (2026) Occupational risk factors for depression and anxiety symptoms: Insights from a large cohort study during and after the SARS-CoV-2 pandemic. PLoS One. https://doi.org/10.1371/journal.pone.0346871
Fasshauer J.M., Frost J., Frese T., Gekle M., Glaser N., Heuser M., Hoell J.I., Massag J., Moor I., Pfrommer L.R., Schüz B., Tüscher O., Mikolajczyk R. & Opel N. (2026) Phenotypic overlap of mental health impairment in post-COVID condition and depressive disorders: Insights from the DigiHero cohort. Journal of Affective Disorders, 406, 121699. https://doi.org/10.1016/j.jad.2026.121699
Frost J., Klee B., Diexer S., Meyer-Schlinkmann K. M., Gottschick C., Rosendahl J., Gekle M., Moritz S., Hettmer S., Hoell J. I., Moor I., Frese T., Binder M., Dierks C. & Mikolajczyk R. (2026) Comparing definitions of SARS-CoV-2 infection in a prospective household transmission study. Journal of Infection and Public Health, 19(2), 103069. https://doi.org/10.1016/j.jiph.2025.103069
Frost J., Peter F., Glaser N., Pfrommer L.R., Fasshauer J.M., Opel N., Gekle M., Behrens T., Tüscher O. & Mikolajczyk R. (2026) Comparison of new and recurring post-acute infection syndrome – results from a German population-based cohort. Scientific Reports, 16, 28492. https://doi.org/10.1038/s41598-026-70451-3
Frost J., Peter F., Glaser N., Frese T., Heuser M., Gekle M., Girndt M., Opel N., Behrens T., Karch A., Muellmann S., Zeeb H., Tüscher O. & Mikolajczyk R. (2026) Postinfektiöse Syndrome in der Post-Pandemie-Phase in der deutschen Allgemeinbevölkerung. Deutsches Ärzteblatt, 123(19). https://doi.org/10.3238/arztebl.m2026.0134
Heinken C., Muellmann S., Brand T., Behrens T., Casjens S., Spallek J., Frost J., Glaser N., Opel N., Massag J., Mikolajczyk R., Gekle M., Moor I., Tüscher O., Heuser M., Schüz B. & Zeeb H. (2026) Heat exhaustion, domestic heat exposure and socioeconomic disparities among older adults: a cross-sectional mediation analysis from Germany. International Journal for Equity in Health. https://doi.org/10.1186/s12939-026-02934-8
Klee B., Diexer S., Glaser N., Gottschick C., Frost J., Massag J., Pfrommer L.R., Herrmann T., Purschke O., Schmidt A., Dierks C., Frese T., Gekle M., Girndt M., Hettmer S., Heuser M., Höll J.I., Moor I., Rosendahl J., Sedding D., Behrens T., Casjens S., Hoffmann S., Karch A., Muellmann S., Opel N., Scherag A., Schüz B., Spallek J., Spallek L., Steinmann L.A., Walter M., Zeeb H. & Mikolajczyk R. (2026) Prospective cohort study for digital health research in Germany (DigiHero): objectives, design and baseline characteristics. European Journal of Epidemiology. https://doi.org/10.1007/s10654-026-01454-7
Monstadt A., Friedrich Y., Rottstädt F., Weiss M., Behrens T., Casjens S., Frost J., Massang J., Moor I., Opel N., Pfrommer L.R., Schüz B., Scherag A., Walter M., Mikolajczyk R. & Croy I. (2026) Multidomain correlates of burnout: A population-based study using supervised machine learning. Social Psychatry and Psychiatric Epidemiology. https://doi.org/10.1007/s00127-026-03113-4
Conference proceedings
Behrens T. et al.(2026). Are occupational factors the missing link? An analysis from the DigiHero online study. Presentation at: 21th Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Behrens T. et al.(2026). Do occupational factors mediate the association of shiftwork with mental health? Conference poster at: 19th European Public Health Conference, November 2026, Bilbao
Burek K. et al. (2026). Hitzebedingte Belastungen am Arbeitsplatz – Ergebnisse einer deutschlandweiten Befragung unter Beschäftigten. Conference poster at: DGUV Forum Forschung der Unfallversicherungsträger 2026, October 2026, Bad Münstereifel
Casjens S. et al. (2026). Berufliche Risikofaktoren für Depressions- und Angstsymptome: Erkenntnisse aus der bevölkerungsbasierten Kohortenstudie DigiHero. Presentation at: 66. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V., March 2026, München
Casjens S. et al. (2026). Berufliche Risikofaktoren und mentale Gesundheit: Ergebnisse aus der deutschlandweiten DigiHero-Kohorte. Conference poster at: DGUV Forum Forschung der Unfallversicherungsträger 2026, October 2026, Bad Münstereifel
Frost J. et al. (2026). Comparison of new and recurring post-acute infection syndrome – results from a German population-based cohort. Conference poster at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Frost J. et al. (2026). Detecting symptom clusters in post-COVID condition – a multi-analyst study in two large German cohorts. Presentation at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Frost J. et al. (2026). Detecting symptom clusters in post-COVID condition – a multi-analyst study in two large German cohorts. Conference poster at: Joint Conference – 70th Society for Social Medicine & Population Health Conference / European Congress of Epidemiology 2026, September 2026, London
Glaser N., Frost J., Schmidt A., Peter F., Hovanec J., Spallek L. & Mikolajczyk R. (2026). A new large digital Cohort in Germany – experiences from the DigiHero study. Workshop at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Glaser N. et al. (2026). Vaccine-induced immunity partially reduces severity of symptoms during non-hospitalized acute respiratory infections. Presentation at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Glaser N. et al. (2026). Occurrence of acute respiratory infections (ARI) over the course of two consecutive winters. Conference poster at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Glaser N. et al. (2026). Vaccine-induced immunity reduces severity of symptoms during non-hospitalized acute respiratory infections. Conference poster at: Joint Conference – 70th Society for Social Medicine & Population Health Conference / European Congress of Epidemiology 2026, September 2026, London
Peter F., Pfrommer L.R. et al. (2026). Stigmatisierungserfahrungen bei Long-/Post-COVID-Betroffenen: Deskriptive Ergebnisse einer bevölkerungsbasierten Kohorte in Deutschland. Auswertung im Rahmen des Projektes „VIBES – Versorgungssituation, Versorgungsinanspruchnahme und Bedarfsanalyse von Patient:innen mit post-viralen Syndromen am Beispiel von Post-COVID“ (Förderung durch Gemeinsamer Bundesausschuss – Innovationsausschuss). Conference poster at: Deutscher Kongress für Psychosomatische Medizin und Psychotherapie, March 2026, Berlin
Pfrommer L.R. et al. (2026). Regionale Unterschiede im mentalen Wohlbefinden in Deutschland: Eine kohortenbasierte Analyse von MDS- und Raumstrukturdaten. Presentation at: 3. Early-Career-Scientist-Kongress des Deutschen Zentrums für Psychische Gesundheit (DZPG), February 2026, Berlin
Pfrommer L.R., Peter F. et al. (2026). Private Gesundheitsleistungen bei Post-COVID-Betroffenen in Deutschland: Inanspruchnahme und finanzielle Belastung in einer bevölkerungsbasierten Kohorte. Auswertung im Rahmen des Projektes „VIBES – Versorgungssituation, Versorgungsinanspruchnahme und Bedarfsanalyse von Patient:innen mit post-viralen Syndromen am Beispiel von Post-COVID“ (Förderung durch Gemeinsamer Bundesausschuss – Innovationsausschuss). Conference poster at: Deutscher Kongress für Psychosomatische Medizin und Psychotherapie, March 2026, Berlin
Pfrommer L.R. et al. (2026). Regional Differences in Mental Health in Germany: Analysis of the Minimal Data Set and Spatial Indicators in the DigiHero Cohort. Conference poster at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Schmidt A. et al. (2026). Benchmarking DigiHero: Comparing a web-based health cohort with census data and established population-based studies with German samples. Conference poster at: 21st Annual Meeting of the German Society for Epidemiology (DGEpi e. V.), September 2026, Ulm
Weitere Arbeiten
…
2025
Peer-reviewed
Glaser, N., Diexer, S., Klee, B., Massag, J., Pfrommer, L. R., Purschke, O., Binder, M., Frese, T., Girndt, M., Hoell, J. I., Moor, I., Rosendahl, J., Gekle, M., Sedding, D., Gottschick, C., Mikolajczyk, R. (2025) Duration of mild acute SARS-CoV-2 infections with Omicron depending on previous vaccinations and infections – Using data of the German DigiHero cohort study from post-pandemic winters 2022/2023 and 2023/2024. J Infect Public Health, 18(6), 102746. https://doi.org/10.1016/j.jiph.2025.102746
Conference proceedings
Frost, J. et al. (2025). SARS-CoV-2 antibody dynamics and waning as a component of transmission modelling. Conference poster at: 3rd (Inter-)National Conference on Infectious Disease Modeling, February 2025, Berlin
Frost J., Pfrommer L.R. et al. (2025). Symptom-specific recovery from Post-COVID over extended follow-up intervals: a longitudinal digital cohort study. Presentation at: 20. Jahrestagung der Deutschen Gesellschaft für Epidemiologie, September 2025, Münster
Frost J. et al. (2025). Investigating consistency of results in the context of COVID-19 and post-COVID – comparison of two large German cohorts. Conference poster at: 20. Jahrestagung der Deutschen Gesellschaft für Epidemiologie, September 2025, Münster
Frost J. et al. (2025). Increasing response to questionnaires in a digital health cohort using non-monetary motivational incentives: a randomised factorial trial. Presentation at: Herbstworkshop der Arbeitsgruppen Statistische Methoden in der Medizin (IBS-DR), Statistische Methoden in der Epidemiologie (IBS-DR, DGEpi, DGSMP), Statistische Methoden in der klinischen Forschung (GMDS), Epidemiologische Methoden (DGEpi, GMDS, DGSMP) und der Querschnittsinitiative Causal Inference (DGEpi), November 2025, Bielefeld
Glaser N., Frost J., Herrmann T., Moor I., Spallek L., Hoffmann S., Spallek J., Behrens T., Casjens S., Müllmann S., Schüz B., Steinmann L.-A., Opel N., Mikolajczyk R. (2025). A new large digital Cohort in Germany – experiences from the DigiHero study. Symposium at: 70. Jahrestagung der Deutschen Gesellschaft für Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), September 2025, Jena
Klee B. et al. (2025). Transmission of respiratory infections within households – results from the German DigiHero study. Presentation at: 20. Jahrestagung der Deutschen Gesellschaft für Epidemiologie, September 2025, Münster
Pfrommer L.R., Massag J. et al. (2025). Erfassung der psychischen Gesundheit in der DigiHero Studie. Conference poster at: 2. Jahrestreffen des Deutschen Zentrums für Psychische Gesundheit (DZPG), September 2025, Bochum
Steinmann, L. A. et al. (2025). Urbanicity and mental health in the DigiHero-Cohort. Presentation at: 2. Early Career Scientists-Kongress des Deutschen Zentrums für Psychische Gesundheit, February 2025, Jena
Other
…
2024
Peer-reviewed
Diexer, S., Klee, B., Gottschick, C., Broda, A., Purschke, O., Binder, M., Gekle, M. Girndt, M., Hoell, J. I., Moor, I., Sedding, D., Rosendahl, J. & Mikolajczyk, R. (2024). Insights into early recovery from Long COVID – results from the German DigiHero Cohort. Scientific reports, 14(1), 8569. https://doi.org/10.1038/s41598-024-59122-3
Fischer, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Diexer, S., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Hoell, J. I., Gekle, M., Addo, M. M., Schulze zur Wiesch, J., Mikolajczyk, R., Binder, M. & Schultheiß, C. (2024). SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition. NPJ vaccines, 9(1), 23. https://doi.org/10.1038/s41541-024-00815-1
Glaser, N., Diexer, S., Klee, B., Purschke, O., Binder, M., Frese, T., Girndt, M., Hoell, J. I., Moor, I., Rosendahl, J., Gekle, M., Sedding, D., Mikolajczyk, R. & Gottschick, C. (2024). The contribution of SARS-CoV-2 to the burden of acute respiratory infections in winter season 2022/2023: results from the DigiHero study. International Journal of Infectious Diseases, 144, 107057. https://doi.org/10.1016/j.ijid.2024.107057
Klee, B., Diexer, S., Xu, C., Gottschick, C., Hartmann, C., Meyer-Schlinkmann, K. M., Kuhlmann, A., Rosendahl, J., Binder, M., Gekle, M., Girndt, M., Hoell, J. I., Moor, I., Sedding, D., Moritz, S., Frese, T. & Mikolajczyk, R. (2024). Household transmission of Omicron variant of SARS-CoV-2 under conditions of hybrid immunity – a prospective study in Germany. Infection, 53(1), 221-230. https://doi.org/10.1007/s15010-024-02352-4
Konopka, A., Führer, A., Binder, M., Diexer, S., Frese, T., Gekle, M., Girndt, M., Gottschick, C., Hoell, J. I., Klee, B., Kreilinger, K., Moor, I., Rosendahl, J., Sedding, D., Klusmann, J.-H., Mikolajczyk, R. & Raberger, K. (2024). Child and Adolescent Mental Health in a Period of Fewer COVID-19-Related Restrictions in an Urban Population in Germany. Psychiatry International, 5(4), 718-737. https://doi.org/10.3390/psychiatryint5040050
Pfrommer, L. R., Diexer, S., Klee, B., Massag, J., Gottschick, C., Purschke, O., Binder, M., Frese, T., Girndt, M., Sedding, D., Rosendahl, J., Hoell, J. I., Moor, I., Gekle, M., Allwang, C., Junne F., & Mikolajczyk, R. (2024). Post-COVID recovery is faster after an infection with the SARS-CoV-2 Omicron variant: a population-based cohort study. Infection. https://doi.org/10.1007/s15010-024-02438-z
Steinmann, L. A., Claaß., L. V., Rau, M., Massag, J., Diexer S., Klee, B., Gottschick, C., Binder, M., Sedding, D., Frese. T., Grindt, M., Hoell, J. I., Moor, I., Rosendahl, J., Gekle, M., Mikolajczyk, R. & Opel, N. (2024). Differential associations between SARS-CoV-2 infection, perceived burden of the pandemic and mental health in the German population-based cohort for digital health research. Psychiatry Research, 341, 116140. https://doi.org/10.1016/j.psychres.2024.116140
Zunker, H., Schmieding, R., Kerkmann, D., Schengen, A., Diexer, S., Mikolajczyk, R., Meyer-Hermann, M. & Kühn, M. J. (2024) Novel travel time aware metapopulation models and multi-layer waning immunity for late-phase epidemic and endemic scenarios. PLOS Computational Biology, 20(12), e1012630 https://doi.org/10.1371/journal.pcbi.1012630
Conference proceedings
Frost J. et al. (2024). Challenges in defining an infection in field studies: an example from a prospective household transmission study. Presentation at: Konferenz Gesundheit Gemeinsam, September 2024, Dresden
Glaser, N. et al. (2024). Duration of non-hospitalized acute SARS-CoV-2 first-infections with Omicron depending on previous vaccinations. Conference poster at: Konferenz Gesundheit Gemeinsam, September 2024, Dresden
Massag, J. et al. (2024). Vergleich DigiHero Mental Health Befragungen mit RKI Mental Health Surveillance. Conference poster at: Konferenz Gesundheit Gemeinsam, September 2024, Dresden
Pfrommer, L. et al. (2024). Post-COVID Register: Versorgungsinanspruchnahme und –zufriedenheit. Conference poster at: Konferenz Gesundheit Gemeinsam, September 2024, Dresden
Steinmann, L. A. et al. (2024). Siedlungsstruktur und mentale Gesundheit in der DigiHero-Kohorte. Presentation at: Kongress der Deutschen Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde, November 2024, Berlin
Other
Broda, A., Klee, B., Diexer, S., Massag, J. & Mikolajczyk, R. (2024). DigiHero – Populationsbasierte Kohortenstudie für digitale Gesundheitsforschung in Deutschland. Ärzteblatt Sachsen-Anhalt 0102/2024. https://t1p.de/mf-0102-24
2023
Peer-reviewed
Diexer, S., Klee, B., Gottschick, C., Xu, C., Broda, A., Purschke, O., Binder, M., Frese, T., Grindt, M., Hoell, J. I., Moor, I., Gekle, M. & Mikolajczyk, R. (2023). Association between virus variants, vaccination, previous infections, and post-COVID-19-risk. International Journal of Infectious Diseases, 136, 14-21. https://doi.org/10.1016/j.ijid.2023.08.019
Gottschick, C., Diexer, S., Massag, J., Klee, B., Broda, A., Purschke, O., Binder, M., Sedding, D., Frese, T., Girndt, M., Hoell, J. I., Michl, P., Gekle, M. & Mikolajczyk, R. (2023). Mental Health in Germany in the first weeks of the Russo-Ukrainian war. BJPsych Open, 9(3), e66. https://doi.org/10.1192/bjo.2023.21
Klee, B., Diexer, S., Sarajan, M. H., Glaser, N., Binder, M., Frese, T., Girndt, M., Sedding, D., Hoell, J. I., Moor, I., Gekle, M., Mikolajczyk, R. & Gottschick, C. (2023). Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort. Vaccines, 11(11), 1640. https://doi.org/10.3390/vaccines11111640
Massag, J., Diexer, S., Klee, B., Costa, D., Gottschick, C., Broda, A., Purschke, O., Opel, N., Binder, M., Sedding, D., Frese, T., Girndt, M., Hoell, J. I., Moor, I., Rosendahl. J., Gekle, M. & Mikolajczyk, R. (2023). Anxiety, depressive symptoms and distress over the course of the war in Ukraine in three federal states in Germany. Frontiers in Psychiatry, 14, 1167615. https://doi.org/10.3389/fpsyt.2023.1167615
Conference proceedings
Diexer, S. et al. (2023). Risk of Post COVID-19 condition in relation to virus variants depending on vaccination and previous infection. Presentation at: 16. Kongress für Infektionskrankheiten und Tropenmedizin (KIT), June 2023, Leipzig
Diexer, S. et al., (2023). Factors and Symptom patterns associated with Recovery from Long COVID. Presentation at: 18. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2023, Würzburg
Glaser, N. et al. (2023). Contribution of COVID-19 to the burden of respiratory infections in autumn/winter 2022/23. Presentation at: 18. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2023, Würzburg
Klee, B. et al. (2023). A prospective study of household transmission of SARS-CoV-2 – Results from the DigiHero study. Presentation at: 18. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2023, Würzburg
Klee, B. et al. (2023). Household transmission of the omicron variant of SARS-CoV-2 – Results from the DigiHero study. Conference poster at: European Scientific Conference on Applied Infectious Diseases Epidemiology (ESCAIDE), November 2023, Barcelona
Massag, J. et al. (2023). Beschwerden nach eine SARS-CoV-2 Infektion – Häufigkeiten und Muster (ABS-DGPM DKPM-2023-00326). Presentation at: Deutscher Kongress für Psychosomatische Medizin und Psychotherapie, May 2023, Berlin
Pfrommer, L. et al. (2023). Patterns of self-reported post-COVID complaints and factors associated with post-COVID recovery: initial results from the emerging post-COVID registry. Conference poster at: Long-COVID Kongress, November 2023, Jena
Steinmann, L. A. et al. (2023). Differential Associations between SARS-CoV-2 Infection, perceived burden of the pandemic and mental health in the German population-based cohort for digital research. Conference poster at: Annual European College of Neuropsychopharmacology Congress, October 2023, Barcelona
Steinmann, L. A. et al. (2023). Assoziationen zwischen SARS-CoV-2-Infektionen und der psychischen Gesundheit in der Bevölkerungsbasierten Kohortenstudie zur digitalen Gesundheitsforschung in Deutschland (DigiHero) unter Berücksichtigung der subjektiven Belastung durch die Pandemie. Conference poster at: Kongress der Deutschen Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN), November/December 2023, Berlin
Other
Fischer, B. (2023). Risiko- und Resilienzfaktoren für die gesundheitsbezogene Lebensqualität 7- bis 10-jähriger Kinder in Halle (Saale) im zweiten Jahr von COVID-19. Master’s thesis at Martin-Luther-University Halle-Wittenberg
2022
Peer-reviewed
Paschold, L., Klee, B., Gottschick, C., Willscher, E., Diexer, S., Schultheiß, C., Simnica, D., Sedding, D., Girndt, M., Gekle, M., Mikolajczyk, R. & Binder, M. (2022). Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-CoV-2 mRNA Vaccination. Frontiers in Immunology, 13, 876306. https://doi.org/10.3389/fimmu.2022.876306
Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Henkes, S.-S., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Hoell, J. I., Gekle, M., Mikolajczyk, R. & Binder, M. (2022). The IL-1β, IL-6 and TNF cytokine triad is associated with post-acute sequelae of COVID-19. Cell Reports Medicine, 3(6), 100663. https://doi.org/10.1016/j.xcrm.2022.100663
Schultheiß, C., Wilscher, E., Paschold, L., Gottschick, C., Klee, B., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Hoell, J. I., Gekle, M., Mikolajczyk, R. & Binder, M. (2022). Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post-acute sequelae of COVID-19. Journal of Medical Virology, 95(1), e28364. https://doi.org/10.1002/jmv.28364
Conference proceedings
Diexer, S. et al. (2022) Mental health in Germany in the first week of the Russo-Ukrainian war: the digital cohort study “DigiHero”. Presentation at: 17. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2022, Greifswald
Gottschick, C. et al. (2022). From paper-based to digital epidemiology: the DigiHero Study. Presentation at: 17. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2022, Greifswald
Massag, J. et al. (2022). Perceived changes in individual well-being during various stages of the COVID-19 pandemic. Presentation at: 17. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2022, Greifswald
Mikolajczyk, R. et al. (2022). Use of SARS-CoV-2 tests during different phases of the COVID-19 pandemic: results of the DigiHero study. Presentation at: 17. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), September 2022, Greifswald